Our Offerings…
We offer computational biosolutions and services in a variety of industry segments. These include the life sciences, in particular the pharmaceutical industry, in a variety of diagnostic and therapeutic segments, as well as agroscience and crop protection. Further industries include power, utilities, chemicals and petrochemicals, in particular biogas and biofuel applications as well as biopolymer products.
Biopharma
We support projects in silico on diagnostic and therapeutic molecule design in the discovery and pre-clinical stages, including traditional hit identification and (hit-to-)lead optimization, with integrated PK/PD, ADME and toxicology criteria. We also help anticipate and mitigate clinical risks throughout the earlier R&D stages.
Biocontrol
Beyond Biopharma, life science is covering agroscience applications, targeting soil, crop and livestock health. We support projects in silico on diagnostic and therapeutic molecule design against crop pests and diseases. This includes, in particular, computational dsRNA and lipid polymer modeling for spray- and host-induced gene silencing therapies addressing viral diseases of affected crops.
Biogas
Besides applications in life science, we enhance and refine biocatalysts for anaerobic digestion processes. We consider a variety of feedstock, targeting stable fermentation processes with optimal biogas output levels. We focus on biotechnical efficiency and commercial viability of biogas businesses and on degradation of substrate contaminants such as plastics, which enter biomass cycles and aggregate in living organisms as microplastics.
Biofuel
Beyond methane, alternative end products can be produced through fermentation. Such products include biofuels such as ethanol and a mix of alkanes, including iso- cyclo- and aromatic alkanes, forming biodiesel and sustainable aviation fuel (SAF). We explore biofuel production with feedstock available in large quantities, such as brown algae (Caribbean pelagic Sargassum) and green macroalgae (Brittanic littoral Ulva). We are predominantly focusing on biochemical, not thermochemical or electrochemical technologies.
Biopolymers
Besides diagnosis, therapy, protection and catalysis of biochemical processes, biomolecules perform many other functions. Some molecular functions are merely supportive, for instance filtering, retention and delivery of other molecules. We design, simulate and validate biopolymers and biocompatible polymers for such support functions in silico, for instance as polymer matrices, membranes, beads, micelles or conjugates. Such polymer support function have applications in a surprisingly large number of industrial segments, far beyond life science, energy and utilities.